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Akcea Therapeutics
Akcea Therapeutics
(AKCA)
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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Tegsedi
Inotersen
2018-10-05
2025-2031
Amyloidosis
,
Familial amyloid neuropathies
Waylivra
Volanesorsen
2019-05-03
Hyperlipoproteinemia type i
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Volanesorsen
cardiovascular abnormalities
,
hyperlipoproteinemia type i
,
syndrome
,
hyperlipidemias
,
hyperlipoproteinemia type v
,
hyperlipoproteinemias
,
lipodystrophy
,
familial partial lipodystrophy
,
hypertriglyceridemia
Inotersen
amyloidosis
,
pregnancy
Sodium chloride
bacterial infections
,
pain
,
respiration disorders
,
vomiting
,
psoriasis
,
autoimmune diseases
,
fibrosis
,
hypoxia
,
renal insufficiency
,
colorectal neoplasms
,
pseudomonas infections
,
common cold
,
breast neoplasms
,
hyperhidrosis
,
respiratory tract infections
,
psoriatic arthritis
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
keloid
,
infectious skin diseases
,
bacterial skin diseases
,
cellulitis
,
pancreatitis
,
acute necrotizing pancreatitis
,
respiratory syncytial viruses
,
inflammatory bowel diseases
,
rabies
,
osteoarthritis
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
familial primary pulmonary hypertension
,
community-acquired infections
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
staphylococcal infections
,
dyslipidemias
,
lipodystrophy
,
hiv-associated lipodystrophy syndrome
,
sepsis
,
healthy volunteers/patients
,
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
melanoma
,
sclerosis
,
tuberculosis
,
malaria
,
dengue
,
cough
,
systemic scleroderma
,
diffuse scleroderma
,
acquired immunodeficiency syndrome
,
falciparum malaria
,
cutaneous malignant melanoma
,
streptococcus agalactiae
,
lymphoma
,
acute lung injury
,
lung injury
,
crohn disease
,
hypersensitivity
,
rhinitis
,
amyloidosis
,
ulcerative colitis
,
kidney transplantation
,
delayed graft function
,
chronic hepatitis b
,
chronic hepatitis
,
hematologic neoplasms
,
skin neoplasms
,
sickle cell anemia
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
glomerulonephritis
,
membranous glomerulonephritis
,
thrombocytopenic purpura idiopathic
,
thrombocytopenia
,
thrombocytopenic purpura
,
purpura
,
follicular lymphoma
,
type 1 diabetes mellitus
,
respiratory distress syndrome
,
severe acute respiratory syndrome
,
disease progression
,
hiv
,
pre-eclampsia
,
eclampsia
,
eosinophilic esophagitis
,
esophagitis
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
atopic dermatitis
,
eczema
,
dermatitis
,
intraabdominal infections
,
soft tissue infections
,
colitis
,
ulcer
,
wounds and injuries
,
cytomegalovirus infections
,
typhoid fever
,
salmonella infections
,
hepatocellular carcinoma
,
liver neoplasms
,
immunologic deficiency syndromes
,
meningitis
,
meningococcal meningitis
,
gonorrhea
,
sexually transmitted diseases
,
covid-19
,
rheumatoid arthritis
,
arthritis
,
herpes simplex
,
hiv infections
,
herpes zoster
,
meningococcal infections
,
stroke
,
premature obstetric labor
,
communicable diseases
,
respiratory tract diseases
,
respiratory syncytial virus infections
,
virus diseases
,
systemic lupus erythematosus
,
muscle spasticity
,
overactive urinary bladder
,
hepatitis b
,
hepatitis
,
hepatitis a
,
neoplasm metastasis
,
carcinoma
,
kidney diseases
,
urinary tract infections
,
pyelonephritis
,
pulmonary eosinophilia
,
nasal polyps
,
polyps
,
rhinosinusitis
,
urinary incontinence
,
enuresis
,
bone fractures
,
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
lung neoplasms
,
small cell lung carcinoma
,
chronic renal insufficiency
,
anemia
,
hypereosinophilic syndrome
,
syndrome
,
churg-strauss syndrome
,
granulomatosis with polyangiitis
,
systemic vasculitis
,
influenza in birds
,
eosinophilia
,
abdominal obesity
,
myositis
,
human influenza
,
asthma
,
chronic obstructive pulmonary disease
,
infections
,
lung diseases
,
obstructive lung diseases
,
diabetes mellitus
,
hypertension
,
type 2 diabetes mellitus
,
nausea
,
respiratory aspiration
,
whooping cough
,
diphtheria
,
diphtheria-tetanus-acellular pertussis vaccines
,
skin care
,
skin diseases
,
wound healing
,
dentin sensitivity
,
photosensitivity disorders
,
photoallergic dermatitis
,
dental plaque
,
immunologic tests
,
sarcoidosis
,
pneumonia
,
inflammation
,
cardiovascular diseases
,
health risk behaviors
,
vascular stiffness
,
yellow fever
Nepidermin
breast neoplasms
,
carcinoma
,
neoplasms
,
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
non-small-cell lung carcinoma
,
neoplasm metastasis
,
myofascial pain syndromes
,
fibromyalgia
,
syndrome
,
hemangioma
,
port-wine stain
,
capillary hemangioma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
melanoma
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
healthy volunteers/patients
Pelacarsen
renal insufficiency
,
liver diseases
,
hepatic insufficiency
,
healthy volunteers/patients
,
aortic valve stenosis
,
pathologic constriction
,
cardiovascular diseases
,
hyperlipidemias
,
hyperlipoproteinemias
,
atherosclerosis
,
myocardial infarction
,
acute coronary syndrome
,
dyslipidemias
,
inflammation
,
infarction
,
genetic polymorphism
VUPANORSEN
healthy volunteers/patients
,
hypertriglyceridemia
,
hyperlipidemias
,
hyperlipoproteinemias
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
lipodystrophy
,
familial partial lipodystrophy
,
liver diseases
,
type 2 diabetes mellitus
,
diabetes mellitus
,
non-alcoholic fatty liver disease
,
fatty liver
,
hyperlipoproteinemia type v
,
syndrome
,
hyperlipoproteinemia type i
,
dyslipidemias
,
homozygous familial hypercholesterolemia
Endocrine
breast neoplasms
Immunoglubulins
amyloidosis
,
familial amyloid neuropathies
,
covid-19
Trinessa
infections
,
hiv infections
,
acquired immunodeficiency syndrome
,
asthma
,
bacterial infections
,
type 2 diabetes mellitus
,
renal cell carcinoma
,
human influenza
,
healthy volunteers/patients
,
anemia
,
respiratory tract infections
,
acute coronary syndrome
,
embryo transfer
,
vivax malaria
,
premature obstetric labor
,
vomiting
,
nausea
,
alzheimer disease
,
diabetes mellitus
,
atrial fibrillation
,
atherosclerosis
,
tuberculosis
,
pulmonary tuberculosis
,
lung diseases
,
chronic obstructive pulmonary disease
,
obstructive lung diseases
Tqj230
liver diseases
,
hepatic insufficiency
,
healthy volunteers/patients
,
aortic valve stenosis
,
pathologic constriction
,
cardiovascular diseases
,
hyperlipidemias
,
hyperlipoproteinemias
,
atherosclerosis
,
myocardial infarction
,
acute coronary syndrome
,
dyslipidemias
,
inflammation
,
infarction
,
genetic polymorphism
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